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KMID : 0381919760060010009
Korean Journal of Microscopy
1976 Volume.6 No. 1 p.9 ~ p.20
Histochemical and Ultrastructural Investigation of the Mucus Containing Cells of the Gastrointestinal Tract in the Mice


Abstract
The present study was performed to clarify the histochemical compositions¢¥ and fine structure of the mucus secreting cells in the gastrointestinal mucosa of normal mice.
The mucus cells in the surface epithelium of stomach body had neutral mucin and some quantity of weak acid mucin. And the mucus cells in gastric pits and mucus neck cells had neutral mucin.
The goblet cells in villial epithelium of small intestine contain strong acid sulfated mucin as their main content and a little of neutral mucopolysaccharide. However, the goblet cells in intestinal glands-Liberkuhn crypt were confirmed to contain non-sulfated weak acid mucin.
The goblet cells in the surface epithelium of colon had the same component as the small intestine did. But the cells in the crypts of colon contained neutral and weak acid mucin as their main contents.
The majority of secretory granules of the surface epithelial cells of the stomach body had high electron density, and some granules with low electron density appeared too. While the mucin granules in the mucus neck cells were low in its electron density, and some of those granules were frequently found to have dense core in them.
Secretary ,granules in goblet cells of small and large intestines had low electron density, The ¢¥mode of secretion in mucin-containing cells in gastro-intestinal tract was found to be merocrine.
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